Influence of ascorbic acid on BUN, creatinine, resistive index in canine renal ischemia-reperfusion injury
نویسندگان
چکیده
منابع مشابه
Influence of ascorbic acid on BUN, creatinine, resistive index in canine renal ischemia-reperfusion injury
Renal ischemia as a course of renal transplantation is a common cause of renal dysfunction as renal failure. The purpose of this study was to investigate the influence of ascorbic acid on blood urea nitrogen (BUN), creatinine (Cr) and resistive index (RI) for dog models with renal ischemia-reperfusion (I/R) injury. Renal ischemia was induced on 6 Beagle dogs. The left kidney was exposed to norm...
متن کاملAttenuation of ischemia-reperfusion injury by ascorbic acid in the canine renal transplantation
This study examined the effects of ascorbic acid on the attenuation of an ischemia-reperfusion (I/R) injury after a canine renal transplantation. Eight beagle dogs were subjected to a renal auto-transplantation followed by the administration of ascorbic acid (treatment group) and the same amount of vehicle (physiological saline, control group). Blood samples were collected from these dogs to pe...
متن کاملThe Effect of Ascorbic Acid on Renal Function in Dogs with Ischemia Reperfusion Injury Kisani
The effect of ascorbic acid on renal function in dogs subjected to ischemia reperfusion injury was investigated. Six dogs with a mean weight of 10 kg (range 8 11 kg) were used in the study. The dogs were administered ascorbic acid (treatment group) and the same volume of normal saline (control group).This administration was followed by reperfusion. Nephrectomy was carried out on the right kidne...
متن کاملAmelioration of rat renal ischemia/reperfusion injury by L-Nil
Introduction: Ischemia/reperfusion (IR) injury involves a complex interrelated sequence of events. High levels of nitric oxide (NO) are generated with inducible form of nitric oxide synthase (iNOS) leading to the renal IR injury and glutathione (GSH) depletion. The present study was designed to investigate the effect of L-Nil (N6- (1-Iminoethyl)-L- lysine.hydrochloride), a selective inhibito...
متن کاملCombination Antioxidant Effect of Erythropoietin and Melatonin on Renal Ischemia-Reperfusion Injury in Rats
Objective(s): Renal ischemia reperfusion (IR) contributes to the development of acute renal failure (ARF). Oxygen free radicals are considered to be principal components involved in the pathophysiological tissue alterations observed during renal IR. The purpose of this study was to investigate the effect of co-administration of melatonin (MEL) and erythropoietin (EPO), potent antioxidant and ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Veterinary Science
سال: 2006
ISSN: 1229-845X
DOI: 10.4142/jvs.2006.7.1.79